DC 2 Novel green technologies and methods for low-environmental impact and low-carbon processes in APIs, pharmaceuticals and nutraceuticals manufacturing

https://euraxess.ec.europa.eu/jobs/139567

The advertised doctoral position (DC2) will be carried out at MyBiotech GmbH over a period of 36 months. The recruited researcher will be supervised by Dr. Nazende Günday-Türeli and work in the department Research and Development, led by Dr. Akif Emre Türeli. The doctoral candidate will be registered for the PhD programme at Saarland University, Germany.

The project will focus on generating methods to be integrated in the green manufacturing technology chains and to be combined on different manufacturing platforms for active pharmaceutical ingredients, pharmaceuticals or nutraceuticals. Encapsulation of valuable chemicals of pharmaceutical and nutraceutical importance will be employed as Proof-of-Concept (PoC) for the suggested manufacturing technology. Unlike conventional methods for production, continuous microreactors will be employed as a green technology for low-environmental impact and low-emission processes. Effect of process parameters on Critical Quality Attributes (CQAs) will be evaluated following a Quality-by-Design strategy for process optimization purposes.

The main working tasks of the advertised position are

(1) Established green drug delivery system manufacturing protocols by innovative continuous manufacturing technologies

(2) Determination of interdependency of CQAs and process parameters

(3) Encapsulation of lipophilic actives to protect from degradation, improve its solubility, bioavailability and stability.

In the frame of the research project, short term (secondment) visits at other partners premises are envisioned. As per call requirements, candidate will spend at least half of the total contract time in a non-academic environment.