
Saarland University
Germany
DC 4 Spinning disc system-based approaches for green manufacturing of innovative drug delivery systems
The advertised doctoral position will be carried out at Saarland University over a period of 36 months. The recruited researcher will be supervised by Prof. Dr. Marc Schneider and work in the department of Biopharmaceutics and Pharmaceutical Technology, led by Prof. Dr. Marc Schneider. The doctoral candidate will be registered for the PhD programme at Saarland University, Germany.
The project will focus on the optimisation and application of spinning disc system-based approaches for manufacturing innovative drug delivery systems both on lab and pilot scale. This technology not only enables the control over process parameters during manufacturing, but also potentially reduces the manufacturing time, number of manufacturing steps and use of organic solvents, thus is a greener alternative. The potential of this technology will be analysed by DoE and to be coupled with other microfluidic systems for post-production removal of organic solvent efficiently will be also pursued.
The main working tasks of the advertised position are:
(1) Established green drug delivery system manufacturing protocols by SDS
(2) Determination of interdependency of drug delivery system qualities and process parameters on particle size, drug load and drug release
(3) Evaluation results of spinning disc system for efficient organic solvent removal and recycling.
In the frame of the research project, short term (secondment) visits at other partners premises are envisioned. As per call requirements, candidate will spend at least half of the total contract time in a non-academic environment.